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Fluorescence in situ hybridization using the subtelomeric 11q probe as a diagnostic tool for congenital thrombocytopenia

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References

  1. Germeshausen M, Ballmaier M, Welte K (2006) MPL mutations in 23 patients suffering from congenital amegakaryocytic thrombocytopenia: the type of mutation predicts the course of the disease. Human Mutat 27(3):296

    Article  Google Scholar 

  2. Penny LA, Dell’Aquila M, Jones MC, Bergoffen J, Cunniff C, Fryns JP, Grace E, Graham JM Jr, Kousseff B, Mattina T (1995) Clinical and molecular characterization of patients with distal 11q deletions. Am J Hum Genet 56(3):676–683

    PubMed  CAS  Google Scholar 

  3. Grossfeld PD, Mattina T, Lai Z, Favier R, Jones KL, Cotter F, Jones C (2004) The 11q terminal deletion disorder: a prospective study of 110 cases. Am J Med Genet 129(1):51–61

    Article  Google Scholar 

  4. Tunnacliffe A, Jones C, Le Paslier D, Todd R, Cherif D, Birdsall M, Devenish L, Yousry C, Cotter FE, James MR (1999) Localization of Jacobsen syndrome breakpoints on a 40-Mb physical map of distal chromosome 11q. Genome Res 9(1):44–52

    PubMed  CAS  Google Scholar 

  5. Gangarossa S, Mattina T, Romano V, Milana G, Mollica F, Schiliro G (1996) Micromegakaryocytes in a patient with partial deletion of the long arm of chromosome 11 [del(11)(q24.2qter)] and chronic thrombocytopenic purpura. Am J Med Genet 62(2):120–123

    Article  PubMed  CAS  Google Scholar 

  6. Gadzicki D, Baumer A, Wey E, Happel CM, Rudolph C, Tönnies H, Neitzel H, Steinemann D, Welte K, Klein C, Schlegelberger B (2005) Jacobsen syndrome and Beckwith–Wiedemann syndrome caused by a parental pericentric inversion inv(11)(p15q24). Ann Hum Genet (in press). DOI 10.1111/j.1469-1809.2006.00271.x

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Acknowledgements

This study was supported by BMBF grant no. 01GM0307 “Congenital Bone Marrow Failure.” We thank G. Teicke for her help in preparing the manuscript and Maike Hagedorn, Melanie Schoop, Jennifer Espenkötter, Willi Arndt, Markus Meyer, and Marcel Tauscher for their excellent technical support.

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Authors and Affiliations

  1. Institute of Cell and Molecular Pathology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany

    G. Göhring, D. Steinemann & B. Schlegelberger

  2. Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Freiburg, Freiburg, Germany

    C. Hanke, C. Kratz, U. Kontny & C. M. Niemeyer

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  1. G. Göhring
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  2. C. Hanke
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  3. C. Kratz
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  4. U. Kontny
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  5. D. Steinemann
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  6. C. M. Niemeyer
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  7. B. Schlegelberger
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Correspondence to G. Göhring.

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Göhring, G., Hanke, C., Kratz, C. et al. Fluorescence in situ hybridization using the subtelomeric 11q probe as a diagnostic tool for congenital thrombocytopenia. Ann Hematol 85, 883–885 (2006). https://doi.org/10.1007/s00277-006-0177-2

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  • DOI: https://doi.org/10.1007/s00277-006-0177-2

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