Skip to main content
Log in

Carcinoids of the rectum: An evaluation of 1271 reported cases

  • Original Articles
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

The present study was conducted to evaluate the current status of rectal carcinoids from multiple systemic aspects, based on extensive information provided by 1271 cases cited in 465 international articles published since 1912. Each case report was carefully read, computerized, and analyzed by the gut-pancreatic endocrinoma analysis system (Niigata Registry). To avoid case duplication, cases without individual identification, such as the age and sex of the patient, and those with identical clinical and laboratory data and institutes of source, were excluded. Where appropriate, selected cases from an overall gastrointestinal (GI) series consisting of 4461 cases similarly documented in the same Registry were referred to for comparison. The representative characteristics of rectal carcinoids consisted of a male preponderance, small-sized tumors of 10 mm or less at detection, predominant submucosal invasion with a relatively high incidence of metastases, a high incidence of hematogenous spread, a predominant histology of the B-type growth pattern, a low rate of silver reactivity, the infrequent association of carcinoid syndrome, and a relatively high rate of mortality within 5 years after removal of the lesions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Sauven F, Ridge JA, Quan SH, Sigurdson ES (1990) Anorectal carcinoid tumors. Is aggressive surgery warranted? Ann Surg 211:67–71

    CAS  PubMed  Google Scholar 

  2. Soga J (1994) Carcinoid tumors: A statistical analysis of a Japanese series of 3126 reported and 1180 autopsy cases. Acta Med Biol 42:87–102

    Google Scholar 

  3. Caldarola VT, Jackman RJ, Moertel CG, Dockerty MB (1964) Carcinoid tumors of the rectum. Am J Surg 107:844–849

    Article  CAS  PubMed  Google Scholar 

  4. Davis Z, Moertel CG, McIlrath DC (1973) The malignant carcinoid syndrome. Surg Gynecol Obstet 137:637–644

    CAS  PubMed  Google Scholar 

  5. Soga J (1982) Carcinoids of the rectum. Tumors of the carcinoid family—Urgut endocrinomas. Acta Med Biol 29:157–201

    Google Scholar 

  6. Sanders RJ (1973) Carcinoids of the gastrointestinal tract. Thomas, Springfield

    Google Scholar 

  7. Cheek RC, Wilson H (1970) Carcinoid tumors. In: Wilson H, Cheek RC, Sherman RT, Storer EH (eds) Carcinoid tumors [Cur Probl Surg]. Year Book, Chicago, pp 4–31

    Google Scholar 

  8. Saltykow S (1912) Über die Genese der “Karzinoiden Tumoren”, sowie der “Adenomyome” des Darmes. Beitr Path Anat 64:559–594

    Google Scholar 

  9. Horn Jr RC (1949) Carcinoid tumors of the colon and rectum. Cancer 2:819–837

    Google Scholar 

  10. Godwin JD II (1975) Carcinoid tumors. An analysis of 2837 cases. Cancer 36:560–569

    PubMed  Google Scholar 

  11. Freund SJ (1957) Carcinoid tumor of the rectum. A statistical study. Am J Surg 93:67–73

    Article  CAS  PubMed  Google Scholar 

  12. Bates Jr HR (1962) Carcinoid tumors of the rectum. Dis Colon Rectum 5:270–280

    PubMed  Google Scholar 

  13. Bates Jr HR (1966) Carcinoid tumors of the rectum. A statistical review. Dis Colon Rectum 9:90

    PubMed  Google Scholar 

  14. Soga J, Kohro T, Tazawa K, Kanahara H, Sano M, Sakashita T, Tajima K, Morooka H, Karaki Y (1975) Argyrophil cell microneoplasia in the Mastomys' stomach—An observation on early carcinoid formation. J Natl Cancer Inst 55:1001–1006

    CAS  PubMed  Google Scholar 

  15. Soga J, Tazawa K (1971) Pathologic analysis of carcinoids. Histologic reevaluation of 62 cases. Cancer 28:990–998

    CAS  PubMed  Google Scholar 

  16. Johnson LA, Lavin P, Moertel CG, Weiland L, Dayal Y, Doos WG, Geller SA, Cooper HS, Nime F, Massé S, Simson IW, Sumner H, Fölsch E, Engstrom P (1983) Carcinoids: The association of histologic growth pattern and survival. Cancer 51:882–889

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Soga, J. Carcinoids of the rectum: An evaluation of 1271 reported cases. Surg Today 27, 112–119 (1997). https://doi.org/10.1007/BF02385898

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02385898

Key words

Navigation