Short CommunicationMybl2(Bmyb) Maps to Mouse Chromosome 2 and Human Chromosome 20q13.1☆
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Cited by (16)
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2007, Pharmacological ResearchIn silico chromosomal clustering of genes displaying altered expression patterns in ovarian cancer
2005, Cancer Genetics and CytogeneticsCitation Excerpt :Pgrn is highly expressed in aggressive cancer cell lines and tissues, including ovarian cancer [48]. The MYBL2 (20q13.1) gene belongs to the MYB family of transcription factor genes and plays an essential role during cell cycle progression [49]. The gene was detected as amplified in a small fraction of breast cancers [50,51].
Association of 20q13.2 copy number changes with the advanced stage of ovarian cancer - Tissue microarray analysis
2005, European Journal of Obstetrics and Gynecology and Reproductive BiologyAnalysis of genetic alterations in salivary gland tumors by comparative genomic hybridization
2001, Cancer Genetics and CytogeneticsNovel genomic imbalances in b-cell splenic marginal zone lymphomas revealed by comparative genomic hybridization and cytogenetics
2001, American Journal of PathologyCitation Excerpt :However gains of 20q have been observed in solid tumors such as colorectal carcinoma,41,42 breast,43 bladder,44 ovarian,45 and pancreatic cancer.46 Several candidate genes have been identified on 20q: the cellular apoptosis susceptibility (CAS) gene;47 BTAK, a putative serine/threonine kinase gene;48 AIB1, a steroid receptor co-activator gene;49 PTPN1, a nonreceptor tyrosine phosphatase involved in growth regulation;50 as well as MYB12, which encodes a transcription factor and plays an important role in cell cycle progression.51 Regarding gene amplifications, CGH studies are detecting an increased number of high-level DNA amplifications in lymphomas, which were relatively rare in NHL by cytogenetic studies.52
Frequent c-myc and Int-2 overrepresentations in nasopharyngeal carcinoma
2000, Human Pathology
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Mapping data from this article have been deposited in Mouse Genome Database under Accession No. MGD-CREX-485.
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