Regular ArticleCytoskeletal Disruption Accelerates Caspase-3 Activation and Alters the Intracellular Membrane Reorganization in DNA Damage-Induced Apoptosis
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2020, Seminars in Cancer BiologyCitation Excerpt :The execution phase of apoptosis occurs both in the extrinsic and intrinsic pathways of apoptosis. In the execution phase of apoptosis, caspases direct the cell death pathway [123,136]. Mainly caspase 3, 6 and 7 are considered execution caspases, which are present in all cells but are only activated when the initiation process of apoptosis occurs [122].
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