Regular articleINVOLVEMENT OF 26-kDa MEMBRANE-BOUND TUMOUR NECROSIS FACTOR PRECURSOR IN BIDIRECTIONAL FEEDBACK REGULATION ON 17-kDa TUMOUR NECROSIS FACTOR PRODUCTION AFTER STIMULATION BY LIPOPOLYSACCHARIDE
References (0)
Cited by (10)
The cybernetics of TNF: Old views and newer ones
2016, Seminars in Cell and Developmental BiologyCitation Excerpt :Reverse signaling by cell-surface TNF provides another level of control allowing activities of the TNF-producing cells, including the expression of TNF, to be adjusted to the effectiveness of TNF function. One of the main functions of the ‘reverse signals’ emanating from TNF upon its binding to its receptors appears to be inhibition of TNF synthesis [4,83,84]. Among the numerous functional changes induced in cells by TNF and TNF-inducing agents, the induction of cell death is exceptional not only in its functional connotation but also in the mode of its restriction.
- f1
Correspondence to: Gen-Ichiro Soma, Department of Molecular Medicine Takano Hospital 4-2-88 Obiyama, Kumamoto 862, Japan
Copyright © 1998 Academic Press. All rights reserved.