rMETase

Open Access
Simultaneous Targeting of Multiple Hallmarks of Cancer With Recombinant Methioninase, Rapamycin and Chloroquine Is Specific and Synergistic to MiaPaCa-2 Pancreatic-Cancer Cells in Contrast to Hs-27 Normal Fibroblasts
JINSOO KIM, QINGHONG HAN, SHUKUAN LI, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, YUTA MIYASHI, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research November 2025, 45 (11) 4765-4770; DOI: https://doi.org/10.21873/anticanres.17825
Open Access
Combinations of Salmonella typhimurium A1-R, Recombinant Methioninase, and Chloroquine, Each Targeting Fundamental Cancer Hallmarks, Are Selectively Effective on Colon Cancer Cells Compared to Normal Fibroblasts
JINSOO KIM, QINGHONG HAN, SHUKUAN LI, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, YUTA MIYASHI, MING ZHAO, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research September 2025, 45 (9) 3661-3668; DOI: https://doi.org/10.21873/anticanres.17729
Open Access
Super Methotrexate-resistant Osteosarcoma Cells Retain Their Sensitivity to Recombinant Methioninase: Targeting Methionine Addiction to Overcome Extreme Cancer-Chemotherapy Resistance
YUSUKE AOKI, QINGHONG HAN, YUTARO KUBOTA, NORIYUKI MASAKI, YASUNORI TOME, MICHAEL BOUVET, KOTARO NISHIDA and ROBERT M. HOFFMAN

Anticancer Research March 2025, 45 (3) 929-934; DOI: https://doi.org/10.21873/anticanres.17480
Open Access
Selective Synergy of Rapamycin Combined With Methioninase on Cancer Cells Compared to Normal Cells
DANIEL ARDJMAND, YUTARO KUBOTA, MOTOKAZU SATO, QINGHONG HAN, KOHEI MIZUTA, SEI MORINAGA and ROBERT M. HOFFMAN

Anticancer Research March 2024, 44 (3) 929-933; DOI: https://doi.org/10.21873/anticanres.16887
You have access
Effective Metabolic Targeting of Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models with Recombinant Methioninase
KENTARO IGARASHI, KEI KAWAGUCHI, TASUKU KIYUNA, KENTARO MIYAKE, TAKASHI MURAKAMI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, HIROYUKI TSUCHIYA and ROBERT M. HOFFMAN

Anticancer Research September 2017, 37 (9) 4807-4812;

Main menu

User menu

Search

rMETase