Rapamycin

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Simultaneous Targeting of Multiple Hallmarks of Cancer With Recombinant Methioninase, Rapamycin and Chloroquine Is Specific and Synergistic to MiaPaCa-2 Pancreatic-Cancer Cells in Contrast to Hs-27 Normal Fibroblasts
JINSOO KIM, QINGHONG HAN, SHUKUAN LI, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, YUTA MIYASHI, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research November 2025, 45 (11) 4765-4770; DOI: https://doi.org/10.21873/anticanres.17825
Open Access
The Triple Combination of Recombinant Methioninase, Rapamycin, and Chloroquine Synergistically Eradicates HCT116 Colon Cancer Cells
JINSOO KIM, QINGHONG HAN, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research July 2025, 45 (7) 2773-2779; DOI: https://doi.org/10.21873/anticanres.17646
Open Access
Combination of Recombinant Methioninase With Rapamycin or Chloroquine Is Synergistic to Highly Inhibit Triple-negative Breast Cancer Cells In Vitro
JINSOO KIM, QINGHONG HAN, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research May 2025, 45 (5) 1853-1859; DOI: https://doi.org/10.21873/anticanres.17564
Open Access
Highly Synergistic Eradication of 143B Osteosarcoma Cells In Vitro by the Combination of Recombinant Methioninase, Chloroquine, and Rapamycin Targeting Methionine Addiction, Autophagy, and mTOR, Respectively
SEI MORINAGA, QINGHONG HAN, KOHEI MIZUTA, BYUNG MO KANG, MICHAEL BOUVET, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Anticancer Research March 2025, 45 (3) 935-941; DOI: https://doi.org/10.21873/anticanres.17481
Open Access
Selective Synergy of Rapamycin Combined With Methioninase on Cancer Cells Compared to Normal Cells
DANIEL ARDJMAND, YUTARO KUBOTA, MOTOKAZU SATO, QINGHONG HAN, KOHEI MIZUTA, SEI MORINAGA and ROBERT M. HOFFMAN

Anticancer Research March 2024, 44 (3) 929-933; DOI: https://doi.org/10.21873/anticanres.16887
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Simvastatin Induces Autophagy and Inhibits Proliferation in Prostate Cancer Cells
YOSHIYUKI MIYAZAWA, YOSHITAKA SEKINE, DAISUKE OKA, SHUN NAKAZAWA, YUSUKE TSUJI, HIROSHI NAKAYAMA and KAZUHIRO SUZUKI

Anticancer Research December 2023, 43 (12) 5377-5386; DOI: https://doi.org/10.21873/anticanres.16741
Open Access
Oral-recombinant Methioninase in Combination With Rapamycin Eradicates Osteosarcoma of the Breast in a Patient-derived Orthotopic Xenograft Mouse Model
NORIYUKI MASAKI, QINGHONG HAN, CARISSA SAMONTE, NATHANIEL F. WU, CHIHIRO HOZUMI, JUSTIN WU, KOYA OBARA, YUTARO KUBOTA, YUSUKE AOKI, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research November 2022, 42 (11) 5217-5222; DOI: https://doi.org/10.21873/anticanres.16028
Open Access
Chemotherapy Can Synergize With Adoptive Immunotherapy to Inhibit Medulloblastoma Growth
JOSEPH L. LASKY, KATHRYN L. BRADFORD, YUNTAO WANG, YOUNGJU PAK and EDUARD H. PANOSYAN

Anticancer Research April 2022, 42 (4) 1697-1706; DOI: https://doi.org/10.21873/anticanres.15646
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Chloroquine Enhances Rapamycin-induced Apoptosis in MG63 Cells
YOICHI ISHIBASHI, OSAMU NAKAMURA, YOSHIKI YAMAGAMI, HIDEKI NISHIMURA, NATSUKO FUKUOKA and TETSUJI YAMAMOTO

Anticancer Research February 2019, 39 (2) 649-654; DOI: https://doi.org/10.21873/anticanres.13159
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Inhibition of Galectin-1 Sensitizes HRAS-driven Tumor Growth to Rapamycin Treatment
JAMES V. MICHAEL, JEREMY G.T. WURTZEL and LAWRENCE E. GOLDFINGER

Anticancer Research October 2016, 36 (10) 5053-5061;

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