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mTOR

  • Open Access
    Cancer Stem Cells in Glioblastoma: The Role of the mTOR Pathway
    MONICA C. MUREB, SABRINA L. ZELLER, HAYLEN T. ROSBERGER, ERIS SPIROLLARI, MOHAN DAS, SIMON J. HANFT, CHIRAG D. GANDHI and MEENA JHANWAR-UNIYAL
    Anticancer Research July 2025, 45 (7) 2697-2709; DOI: https://doi.org/10.21873/anticanres.17640
  • Open Access
    Reduced Malignancy of Super Methotrexate-resistant Osteosarcoma Cells With Dihydrofolate Reductase Amplification Despite Paradoxical Gain of Oncogenic PI3K/AKT/mTOR and c-MYC expression
    YUSUKE AOKI, YUTARO KUBOTA, NORIYUKI MASAKI, KOYA OBARA, YASUNORI TOME, MICHAEL BOUVET, KOTARO NISHIDA and ROBERT M. HOFFMAN
    Anticancer Research July 2024, 44 (7) 2787-2792; DOI: https://doi.org/10.21873/anticanres.17090
  • You have access
    Down-regulation of ABCB1 in Everolimus-resistant Renal Cell Carcinoma Cells
    YUKO NAKAYAMA, AYA INO, KAZUHIRO YAMAMOTO and KOHJI TAKARA
    Anticancer Research July 2024, 44 (7) 2871-2876; DOI: https://doi.org/10.21873/anticanres.17099
  • You have access
    A Potential Combination of Targeting HSP90 and mTOR in Breast Cancer Cell Growth, Migration, and Invasion Through Inhibiting AKT Phosphorylation and F-actin Organization
    PRASIT SUWANNALERT, PIMCHANOK PANPINYAPORN, PITCHAPA WANTANACHAISAENG, TEERAPAT TEEPPAIBUL, WILUNPLUS KHUMSRI, THIDARAT KOOMSANG, WITCHUDA PAYUHAKRIT and CHONNAPAT NAKTUBTIM
    Anticancer Research June 2024, 44 (6) 2555-2565; DOI: https://doi.org/10.21873/anticanres.17061
  • Open Access
    Selective Synergy of Rapamycin Combined With Methioninase on Cancer Cells Compared to Normal Cells
    DANIEL ARDJMAND, YUTARO KUBOTA, MOTOKAZU SATO, QINGHONG HAN, KOHEI MIZUTA, SEI MORINAGA and ROBERT M. HOFFMAN
    Anticancer Research March 2024, 44 (3) 929-933; DOI: https://doi.org/10.21873/anticanres.16887
  • Open Access
    Molecular Characteristics of Everolimus-resistant Renal Cell Carcinoma Cells Generated by Continuous Exposure to Everolimus
    YUKO NAKAYAMA, DAICHI ENOMOTO, KAZUHIRO YAMAMOTO and KOHJI TAKARA
    Anticancer Research October 2023, 43 (10) 4349-4357; DOI: https://doi.org/10.21873/anticanres.16630
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    Unlocking Synergistic Potential: Enhancing Regorafenib Efficacy in Hepatocellular Carcinoma Through Combination Therapy With 18β-Glycyrrhetinic Acid
    JR-DI YANG, PO-FU YUEH, TSAI LAN LIAO, YING-TZU CHEN, FEI-TING HSU, I-TSANG CHIANG, CHING MING CHANG and WEI-SHU WANG
    Anticancer Research October 2023, 43 (10) 4403-4412; DOI: https://doi.org/10.21873/anticanres.16636
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    Combined Targeting of AKT and mTOR Synergistically Inhibits Formation of Primary Colorectal Carcinoma Tumouroids In Vitro: A 3D Tumour Model for Pre-therapeutic Drug Screening
    DOMINIK NÖRZ, CHRISTINA S. MULLINS, DANIEL J. SMIT, MICHAEL LINNEBACHER, GRITH HAGEL, ALP MIRDOGAN, JACQUELINE SIEKIERA, PATRICK EHM, JAKOB R. IZBICKI, ANDREAS BLOCK, OLE THASTRUP and MANFRED JÜCKER
    Anticancer Research May 2021, 41 (5) 2257-2275; DOI: https://doi.org/10.21873/anticanres.15002
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    Mir-139 Regulates Autophagy in Prostate Cancer Cells Through Beclin-1 and mTOR Signaling Proteins
    ROBERT K. NAM, TANIA BENATAR, YUTAKA AMEMIYA, CHRISTOPHER SHERMAN and ARUN SETH
    Anticancer Research December 2020, 40 (12) 6649-6663; DOI: https://doi.org/10.21873/anticanres.14689
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    Mitochondrial Glutamine Metabolism Determines Senescence Induction After Chemotherapy
    BYUNGJOO KIM, JIHYE GWAK, EUN KYUNG LEE and SEUNG MIN JEONG
    Anticancer Research December 2020, 40 (12) 6891-6897; DOI: https://doi.org/10.21873/anticanres.14712

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