TY - JOUR T1 - High-dose Vitamin C (Ascorbic Acid) Therapy in the Treatment of Patients with Advanced Cancer JF - Anticancer Research JO - Anticancer Res SP - 809 LP - 815 VL - 29 IS - 3 AU - SATOSHI OHNO AU - YUMIKO OHNO AU - NOBUTAKA SUZUKI AU - GEN-ICHIRO SOMA AU - MASAKI INOUE Y1 - 2009/03/01 UR - http://ar.iiarjournals.org/content/29/3/809.abstract N2 - Vitamin C (ascorbic acid, ascorbate) has a controversial history in cancer treatment. Emerging evidence indicates that ascorbate in cancer treatment deserves re-examination. As research results concerning ascorbate pharmacokinetics and its mechanisms of action against tumor cells have been published, and as evidence from case studies has continued to mount that ascorbate therapy could be effective if the right protocols were used, interest among physicians and scientists has increased. In this review, high-dose vitamin C therapy in cancer treatment is re-evaluated. ER -