PT - JOURNAL ARTICLE AU - DONGWEI ZHANG AU - WILLIAM D. WILLIAMS AU - JINPING LAI TI - An Unusual Case of Cecal Mesenteric Dedifferentiated Liposarcoma Involving the Ileocolic Artery Resected by Right Hemicolectomy AID - 10.21873/anticanres.13138 DP - 2019 Jan 01 TA - Anticancer Research PG - 487--490 VI - 39 IP - 1 4099 - http://ar.iiarjournals.org/content/39/1/487.short 4100 - http://ar.iiarjournals.org/content/39/1/487.full SO - Anticancer Res2019 Jan 01; 39 AB - Background: Colonic mesenteric dedifferentiated liposarcoma is a rare entity. Case Report: A 65-year-old male developed a 6 cm diameter right-side intra-abdominal mesenteric mass. A biopsy of the mass was performed and the pathology diagnosis was a spindle cell neoplasm most consistent with low-grade sarcoma. The mass was found to involve the ileocolic vessels in the mesentery on the right side of the abdomen, and therefore the patient received right hemicolectomy with mesenteric mass resection. Pathology confirmed a dedifferentiated liposarcoma (DDLPS) arising in a well-differentiated liposarcoma/atypical lipomatous tumor with myxoid changes. The tumor cells were positive for MDM2 amplification by fluorescence in situ hybridization. After 6 months of follow-up, our patient showed no sign of recurrence. Conclusion: We report an unusual cecal mesenteric DDLPS which was successfully resected by right hemicolectomy. The results suggest that DDLPS should be considered in the differential diagnosis of patients presenting with a spindle cell neoplasm in the mesentery.