TY - JOUR T1 - Essentiality of Imaging Diagnostic Criteria Specific to Rectal Neuroendocrine Tumors for Detecting Metastatic Lymph Nodes JF - Anticancer Research JO - Anticancer Res SP - 505 LP - 510 DO - 10.21873/anticanres.13141 VL - 39 IS - 1 AU - MICHIHIRO KUDOU AU - TOMOHIRO ARITA AU - MASAYOSHI NAKANISHI AU - YOSHIAKI KURIU AU - YASUTOSHI MURAYAMA AU - KATSUTOSHI SHODA AU - TOSHIYUKI KOSUGA AU - HIROTAKA KONISHI AU - RYO MORIMURA AU - ATSUSHI SHIOZAKI AU - HISASHI IKOMA AU - TAKESHI KUBOTA AU - HITOSHI FUJIWARA AU - KAZUMA OKAMOTO AU - EIGO OTSUJI Y1 - 2019/01/01 UR - http://ar.iiarjournals.org/content/39/1/505.abstract N2 - Background/Aim: The present study aimed to clarify an accurate diagnostic method for lymph node metastasis (LN+) in rectal neuroendocrine tumors (rNETs). Patients and Methods: This was a retrospective study of 14 rNETs and 45 rectal adenocarcinoma patients undergoing rectal resection. The short axis of LNs was measured using CT and pathological findings (43 paraffin-fixed LNs in rNETs and 786 LNs in adenocarcinoma). Results: The size of LN+ in CT and pathological findings was smaller in rNETs than adenocarcinoma (p=0.082 and p<0.001, respectively). The AUC values of ROC curves for detecting LN+ using LN sizes on CT were 0.837 for rNETs and 0.885 for adenocarcinoma (Cut-off values: 5 mm for rNETs, 7 mm for adenocarcinoma). rNETs were diagnosed with high accuracy using the cut-off value of rNETs (5 mm) (sensitivity: 80.0%, and specificity: 87.5%). Conclusion: The size of LN+ was smaller in rNETs than in adenocarcinoma, suggesting the essentiality of diagnostic criteria specific for rNETs. ER -