PT  - JOURNAL ARTICLE
AU  - MICHIHIRO KUDOU
AU  - TOMOHIRO ARITA
AU  - MASAYOSHI NAKANISHI
AU  - YOSHIAKI KURIU
AU  - YASUTOSHI MURAYAMA
AU  - KATSUTOSHI SHODA
AU  - TOSHIYUKI KOSUGA
AU  - HIROTAKA KONISHI
AU  - RYO MORIMURA
AU  - ATSUSHI SHIOZAKI
AU  - HISASHI IKOMA
AU  - TAKESHI KUBOTA
AU  - HITOSHI FUJIWARA
AU  - KAZUMA OKAMOTO
AU  - EIGO OTSUJI
TI  - Essentiality of Imaging Diagnostic Criteria Specific to Rectal Neuroendocrine Tumors for Detecting Metastatic Lymph Nodes
AID  - 10.21873/anticanres.13141
DP  - 2019 Jan 01
TA  - Anticancer Research
PG  - 505--510
VI  - 39
IP  - 1
4099  - http://ar.iiarjournals.org/content/39/1/505.short
4100  - http://ar.iiarjournals.org/content/39/1/505.full
SO  - Anticancer Res2019 Jan 01; 39
AB  - Background/Aim: The present study aimed to clarify an accurate diagnostic method for lymph node metastasis (LN+) in rectal neuroendocrine tumors (rNETs). Patients and Methods: This was a retrospective study of 14 rNETs and 45 rectal adenocarcinoma patients undergoing rectal resection. The short axis of LNs was measured using CT and pathological findings (43 paraffin-fixed LNs in rNETs and 786 LNs in adenocarcinoma). Results: The size of LN+ in CT and pathological findings was smaller in rNETs than adenocarcinoma (p=0.082 and p<0.001, respectively). The AUC values of ROC curves for detecting LN+ using LN sizes on CT were 0.837 for rNETs and 0.885 for adenocarcinoma (Cut-off values: 5 mm for rNETs, 7 mm for adenocarcinoma). rNETs were diagnosed with high accuracy using the cut-off value of rNETs (5 mm) (sensitivity: 80.0%, and specificity: 87.5%). Conclusion: The size of LN+ was smaller in rNETs than in adenocarcinoma, suggesting the essentiality of diagnostic criteria specific for rNETs.