RT Journal Article
SR Electronic
T1 A Liposomal Delivery Vehicle for the Anticancer Agent Gossypol
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 2801
OP 2805
VO 28
IS 5A
A1 ZHAI, GUANGXI
A1 WU, JUN
A1 ZHAO, XIAOBIN
A1 YU, BO
A1 LI, HONG
A1 LU, YANHUI
A1 YE, WEIPING
A1 LIN, YOUNG C.
A1 LEE, ROBERT J.
YR 2008
UL http://ar.iiarjournals.org/content/28/5A/2801.abstract
AB Background: Gossypol has recently been identified as a potential anticancer agent. In this study, a novel liposomal formulation is evaluated for delivery of gossypol. Materials and Methods: Gossypol was incorporated into liposomes. The liposomes were characterized for physical and chemical properties and for in vitro cytotoxicity. Results: Gossypol was stably encapsulated in these liposomes and exhibited cytotoxicity towards cancer cells. Conclusion: Liposomes can be used effectively as gossypol carriers.