PT - JOURNAL ARTICLE AU - ZHAI, GUANGXI AU - WU, JUN AU - ZHAO, XIAOBIN AU - YU, BO AU - LI, HONG AU - LU, YANHUI AU - YE, WEIPING AU - LIN, YOUNG C. AU - LEE, ROBERT J. TI - A Liposomal Delivery Vehicle for the Anticancer Agent Gossypol DP - 2008 Sep 01 TA - Anticancer Research PG - 2801--2805 VI - 28 IP - 5A 4099 - http://ar.iiarjournals.org/content/28/5A/2801.short 4100 - http://ar.iiarjournals.org/content/28/5A/2801.full SO - Anticancer Res2008 Sep 01; 28 AB - Background: Gossypol has recently been identified as a potential anticancer agent. In this study, a novel liposomal formulation is evaluated for delivery of gossypol. Materials and Methods: Gossypol was incorporated into liposomes. The liposomes were characterized for physical and chemical properties and for in vitro cytotoxicity. Results: Gossypol was stably encapsulated in these liposomes and exhibited cytotoxicity towards cancer cells. Conclusion: Liposomes can be used effectively as gossypol carriers.