RT Journal Article
SR Electronic
T1 Amelanotic Metastasis of Melanoma Mimicking Ovarian Cancer: A Case Report and Review of the Literature
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 563
OP 566
VO 28
IS 1B
A1 PIETZNER, KLAUS
A1 NOSKE, AURELIA
A1 CHO, CHIE HEE
A1 KIECKER, FELIX
A1 SEHOULI, JALID
YR 2008
UL http://ar.iiarjournals.org/content/28/1B/563.abstract
AB Ovarian manifestation of metastatic amelanotic melanoma is exceptionally rare and can lead to the clinical and even histological misdiagnosis of ovarian cancer. We report on a 35-year-old female patient who presented with bilateral adnexal masses, as well as massive ascites. She underwent laparascopy and multiple biopsies were taken. She was histologically diagnosed with malignant ovarian tumour and was referred for radical surgery. Postoperative final histological examination and immunohistochemical staining of the tumour revealed an amelanotic epithelioid melanoma. Despite the variety of this case, clinicians should be aware of this differential diagnosis when treating ovarian cancer. This report discusses the differential diagnosis and clinical management of both metastatic amelanotic malignant melanoma of the ovary and epithelial ovarian cancer.