TY - JOUR T1 - Subdural Hematoma Associated with Dural Metastasis of Gastric Carcinoma: Report of Two Cases JF - Anticancer Research JO - Anticancer Res SP - 4339 LP - 4344 VL - 27 IS - 6C AU - TAKAO KATSUBE AU - TOMOKO KIKUCHI AU - SOICHI KONNNO AU - MINORU MURAYAMA AU - RIE KOBAYASHI AU - KOTARO KUHARA AU - KAZUHIKO YOSHIMATSU AU - SHUNNICHI SHIOZAWA AU - TAKESHI SHIMAKAWA AU - YOSHIHIKO NARITAKA AU - KENJI OGAWA AU - SHINNJI HAGIWARA AU - MOTOHIKO AIBA Y1 - 2007/11/01 UR - http://ar.iiarjournals.org/content/27/6C/4339.abstract N2 - We treated two cases of a subdural hematoma associated with dural metastasis of gastric cancer, from which both patients died. Case 1: A 60-year-old female patient was hospitalized with a diagnosis of type 4 gastric cancer of the antrum. The patient suddenly collapsed, and, subsequently, left hemiplegia and a depressed level of consciousness were noted. A head computed tomography (CT) scan revealed a subdural hematoma with midline shift. The patient was diagnosed with chronic subdural hematoma and underwent emergency burr hole irrigation. Case 2: A 73-year-old man was diagnosed with type 4 gastric cancer and a total gastrectomy plus splenectomy were performed together with dissection of the N1 and N2 lymph node groups (D2 dissection) in March 2006 (T3, N2, P0, H0, INFγ, ly3, v0, por2). Postoperative adjuvant chemotherapy was performed using oral TS-1; following tests revealed no recurrence in the abdomen. In December 2006, gingival bleeding was noted with disseminated intravascular coagulation (DIC) and 10 days later, the patient was hospitalized with chief complaints of impaired consciousness and anorexia. CT scan revealed a right subdural hematoma with a midline shift. The patient was diagnosed with chronic subdural hematoma and underwent emergency burr hole irrigation and drainage. The dural biopsy of the two cases revealed adenocarcinoma noted in the dural blood vessel. Special staining revealed CEA-positive adenocarcinoma, and a diagnosis of the dural metastasis of gastric cancer was made. These patients' level of consciousness significantly improved postoperatively. However, DIC developed concurrently, and the patients died on the 13th and 14th postoperative day, respectively. Copyright© 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved ER -