RT Journal Article SR Electronic T1 Evaluation of Quality of Life (QOL) in Long-term Survivors of High-grade Osteosarcoma: A Japanese Single Center Experience JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 3621 OP 3624 VO 27 IS 5B A1 TSUKASA YONEMOTO A1 TAKESHI ISHII A1 YOSHIO TAKEUCHI A1 KENJI KIMURA A1 YOKO HAGIWARA A1 SHINTARO IWATA A1 SHIN-ICHIRO TATEZAKI YR 2007 UL http://ar.iiarjournals.org/content/27/5B/3621.abstract AB Background: This study aimed to evaluate the quality of life (QOL) in long-term survivors of high-grade osteosarcoma. Patients and Methods: The QOL of 33 long-term survivors of osteosarcoma was evaluated using the Short Form 36 (SF-36) Health Survey Questionnaire. The patients were divided into a limb-sparing group (14 patients) and an amputation group (19 patients), and the QOL was compared between them. In addition, limb function was assessed using the system for functional evaluation of the limb of the American Musculoskeletal Tumor Society (MSTS score), and the relationship between the MSTS score and SF-36 scores was studied. Results: The QOL of all patients was lower than the national standard concerning physical functioning but was higher than the national standards in the other parameters. The QOL of the limb-sparing group was significantly better than that of the amputation group with regard to social functioning. No significant correlation was noted between the MSTS score and the mental component summary. Conclusion: The QOL of the long-term survivors of osteosarcoma was satisfactory except for physical functioning. Limb-sparing surgery improved the QOL of long-term survivors of osteosarcoma with regard to social functioning, but no correlation was noted between limb function and mental QOL. Copyright© 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved