PT  - JOURNAL ARTICLE
AU  - K. KRAUSS
AU  - C. BACHMANN
AU  - J.T. HARTMANN
AU  - K. SIEGMANN
AU  - K. SOTLAR
AU  - D. WALLWIENER
AU  - J. HUOBER
TI  - Management of Late Recurrence of a Low-grade Endometrial Stromal Sarcoma (LGESS): Treatment with Letrozole
DP  - 2007 Sep 01
TA  - Anticancer Research
PG  - 3477--3480
VI  - 27
IP  - 5B
4099  - http://ar.iiarjournals.org/content/27/5B/3477.short
4100  - http://ar.iiarjournals.org/content/27/5B/3477.full
SO  - Anticancer Res2007 Sep 01; 27
AB  - Low grade endometrial stromal sarcoma (LGESS) is a rare disease. LGESS usually expresses steroidal receptors and is regarded to be hormone-sensitive. Due to the rarity of the tumor, only few case series have been published so far. Here, we report the case of a 36-year-old woman who underwent an abdominal hysterectomy with bilateral salpingo-oophorectomy and adjuvant radiotherapy for a G1 LGESS in 1991. Twelve years later she presented to us with pelvic and peritoneal masses. The patient was treated with letrozole achieving a partial response which is lasting 39 months. Treatment is ongoing. Aromatase inhibitors represent an interesting treatment option for LGESS. Copyright© 2007 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved