RT Journal Article
SR Electronic
T1 Preoperative Serum C-reactive Protein Level in Non-small Cell Lung Cancer
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3001
OP 3004
VO 27
IS 4C
A1 HARA, MASAKI
A1 MATSUZAKI, YASUNORI
A1 SHIMUZU, TETSUYA
A1 TOMITA, MASAKI
A1 AYABE, TAKANORI
A1 ENOMOTO, YUSUKE
A1 ONITSUKA, TOSHIO
YR 2007
UL http://ar.iiarjournals.org/content/27/4C/3001.abstract
AB We evaluated the significance of the preoperative serum C-reactive protein (CRP) level as a prognostic indicator in patients with non-small cell lung cancer (NSCLC). Patients and Methods: Two hundred and three patients who had undergone a curative resection of NSCLC were retrospectively reviewed. Results: The proportion of the tumor size over 3 cm per patient in the CRP-positive group (≥0.5 mg/dL: n=38) was significantly higher than that in the CRP-negative group (<0.5 mg/dL: n=165). The proportion of the adenocarcinoma in CRP-positive group was significantly lower than that in CRP-negative group. The overall and disease specific survival rates in the CRP-positive group were significantly lower than the rates in the CRP-negative group. Based on a multivariate analysis, the preoperative serum CRP level was selected as one of the unfavorable indicators regarding survival. Conclusion: The preoperative serum CRP level is an independent and significant indicator predictive of a poor prognosis in patients with NSCLC.