TY - JOUR T1 - The Distribution and Pathological Staging of Colorectal Cancers in Ethnic Groups JF - Anticancer Research JO - Anticancer Res SP - 2957 LP - 2959 VL - 27 IS - 4C AU - ALOK TIWARI AU - TUN KWAN YEO AU - SOLON RIRIS AU - MOHAMMED MOGHAL AU - SUE WILLIAMS AU - LUKE MELEAGROS Y1 - 2007/07/01 UR - http://ar.iiarjournals.org/content/27/4C/2957.abstract N2 - Background: There is little data on the distribution and histological staging of colorectal cancer in ethnic groups in the United Kingdom. A study to investigate this was undertaken at a hospital serving a multi-ethnic population. Patients and Methods: Case analysis from a prospective database of all colorectal cancers between 2000-2004 was performed. Data was recorded on the distribution of cancer, operative procedures and Dukes' staging. Results: A total of 256 patients (118 females) were diagnosed with colorectal cancer, of whom 214 (83.6%) underwent resection. There were 39 Afro-Caribbeans 66.2 years ± 12.6 years; mean [age±s.d.], 14 Asians 64 years ± 12.6 years, 34 Mediterraneans 67.7 years ± 9.9 years and 176 Caucasian British 74.3 years ± 11.3 years. Right-sided colonic lesions were more frequent in Afro-Caribbeans, whilst left-sided lesions were more frequent in Mediterraneans. The incidence of Dukes' A cancer was high in Mediterraneans whilst Dukes' C cancer was commoner in Caucasians and Afro-Caribbeans. Conclusion: Ethnic patients present with colorectal cancer at significantly younger ages. Afro-Caribbeans have significantly more right-sided and Mediterraneans more left-sided cancer. Afro-Caribbean and Caucasian patients present with more advanced cancer compared to Mediterraneans. This has implications on the investigation, as well as screening in ethnic minority patients. ER -