@article {TIWARI2957, author = {ALOK TIWARI and TUN KWAN YEO and SOLON RIRIS and MOHAMMED MOGHAL and SUE WILLIAMS and LUKE MELEAGROS}, title = {The Distribution and Pathological Staging of Colorectal Cancers in Ethnic Groups}, volume = {27}, number = {4C}, pages = {2957--2959}, year = {2007}, publisher = {International Institute of Anticancer Research}, abstract = {Background: There is little data on the distribution and histological staging of colorectal cancer in ethnic groups in the United Kingdom. A study to investigate this was undertaken at a hospital serving a multi-ethnic population. Patients and Methods: Case analysis from a prospective database of all colorectal cancers between 2000-2004 was performed. Data was recorded on the distribution of cancer, operative procedures and Dukes{\textquoteright} staging. Results: A total of 256 patients (118 females) were diagnosed with colorectal cancer, of whom 214 (83.6\%) underwent resection. There were 39 Afro-Caribbeans 66.2 years {\textpm} 12.6 years; mean [age{\textpm}s.d.], 14 Asians 64 years {\textpm} 12.6 years, 34 Mediterraneans 67.7 years {\textpm} 9.9 years and 176 Caucasian British 74.3 years {\textpm} 11.3 years. Right-sided colonic lesions were more frequent in Afro-Caribbeans, whilst left-sided lesions were more frequent in Mediterraneans. The incidence of Dukes{\textquoteright} A cancer was high in Mediterraneans whilst Dukes{\textquoteright} C cancer was commoner in Caucasians and Afro-Caribbeans. Conclusion: Ethnic patients present with colorectal cancer at significantly younger ages. Afro-Caribbeans have significantly more right-sided and Mediterraneans more left-sided cancer. Afro-Caribbean and Caucasian patients present with more advanced cancer compared to Mediterraneans. This has implications on the investigation, as well as screening in ethnic minority patients.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/27/4C/2957}, eprint = {https://ar.iiarjournals.org/content/27/4C/2957.full.pdf}, journal = {Anticancer Research} }