RT Journal Article
SR Electronic
T1 Angiosarcoma of the Heart: Case Report and Review of the Literature
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 4837
OP 4842
VO 26
IS 6C
A1 BATZIOS, S.
A1 MICHALOPOULOS, A.
A1 KAKLAMANIS, L.
A1 STATHOPOULOS, J.
A1 CHRISTOPOULOU, M.
A1 KOUTANTOS, J.
A1 STATHOPOULOS, G.P.
YR 2006
UL http://ar.iiarjournals.org/content/26/6C/4837.abstract
AB Background: Primary angiosarcoma of the heart is an extremely rare malignant disease. Patients and Methods: A 32-year-old female with primary angiosarcoma of the heart at an advanced stage with lung and bone metastases is presented. The tumor showed extensive expression of c-erb-B2 and a moderate expression of c-kit. Chemotherapy (cisplatin, epirubicin and ifosfamide) was administered. Herceptin as well as glivec were added to the above combination. Results: There was a good partial response and the lung deposits almost disappeared. The duration of response was 6 months. Conclusion: This case of angiosarcoma of the heart is presented because of the extreme rarity of this disease, and its responsiveness to chemotherapy in combination with imatinib and herceptin. Copyright© 2006 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved