RT Journal Article
SR Electronic
T1 Laparoscopic Colorectal Cancer Surgery for Patients With Severe Chronic Heart Failure
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 5645
OP 5648
DO 10.21873/anticanres.16768
VO 43
IS 12
A1 NAKAJO, SHOICHIRO
A1 UEMURA, MAMORU
A1 SEKIDO, YUKI
A1 HATA, TSUYOSHI
A1 HAMABE, ATSUSHI
A1 OGINO, TAKAYUKI
A1 MIYOSHI, NORIKATSU
A1 YAMAMOTO, HIROFUMI
A1 DOKI, YUICHIRO
A1 EGUCHI, HIDETOSHI
YR 2023
UL http://ar.iiarjournals.org/content/43/12/5645.abstract
AB Background/Aim: Laparoscopic surgery with pneumoperitoneum is not usually recommended for patients with heart failure due to the potential risks associated with cardiopulmonary stress. Few studies, however, have directly examined whether a laparoscopic approach can be used safely in patients with severe chronic heart failure. Patients and Methods: We retrospectively evaluated the safety and feasibility of laparoscopic colorectal cancer surgery in 13 patients with severe chronic heart failure, defined as left ventricular ejection fraction <40% and/or brain natriuretic peptide >100 pg/ml (NT-proBNP >400 pg/ml). Intraoperative hemodynamics, including systolic blood pressure, diastolic blood pressure, mean blood pressure, and heart rate, were carefully monitored. Results: The median left ventricular ejection fraction value was 35% (18-62%), and the median brain natriuretic peptide value was 171.7 pg/ml (109.5-961.4 pg/ml). The time-series mean ratio of the patients’ blood pressure and heart rate during surgery indicated that soon after the induction of general anesthesia, mean blood pressure was significantly decreased (p<0.05) from baseline. In all 13 cases, laparoscopic surgery was performed successfully, with no significant complications. Conclusion: The present study showed that laparoscopic surgery for colorectal cancer can be performed safely in patients with severe chronic heart failure.