PT  - JOURNAL ARTICLE
AU  - NAKAJO, SHOICHIRO
AU  - UEMURA, MAMORU
AU  - SEKIDO, YUKI
AU  - HATA, TSUYOSHI
AU  - HAMABE, ATSUSHI
AU  - OGINO, TAKAYUKI
AU  - MIYOSHI, NORIKATSU
AU  - YAMAMOTO, HIROFUMI
AU  - DOKI, YUICHIRO
AU  - EGUCHI, HIDETOSHI
TI  - Laparoscopic Colorectal Cancer Surgery for Patients With Severe Chronic Heart Failure
AID  - 10.21873/anticanres.16768
DP  - 2023 Dec 01
TA  - Anticancer Research
PG  - 5645--5648
VI  - 43
IP  - 12
4099  - http://ar.iiarjournals.org/content/43/12/5645.short
4100  - http://ar.iiarjournals.org/content/43/12/5645.full
SO  - Anticancer Res2023 Dec 01; 43
AB  - Background/Aim: Laparoscopic surgery with pneumoperitoneum is not usually recommended for patients with heart failure due to the potential risks associated with cardiopulmonary stress. Few studies, however, have directly examined whether a laparoscopic approach can be used safely in patients with severe chronic heart failure. Patients and Methods: We retrospectively evaluated the safety and feasibility of laparoscopic colorectal cancer surgery in 13 patients with severe chronic heart failure, defined as left ventricular ejection fraction <40% and/or brain natriuretic peptide >100 pg/ml (NT-proBNP >400 pg/ml). Intraoperative hemodynamics, including systolic blood pressure, diastolic blood pressure, mean blood pressure, and heart rate, were carefully monitored. Results: The median left ventricular ejection fraction value was 35% (18-62%), and the median brain natriuretic peptide value was 171.7 pg/ml (109.5-961.4 pg/ml). The time-series mean ratio of the patients’ blood pressure and heart rate during surgery indicated that soon after the induction of general anesthesia, mean blood pressure was significantly decreased (p<0.05) from baseline. In all 13 cases, laparoscopic surgery was performed successfully, with no significant complications. Conclusion: The present study showed that laparoscopic surgery for colorectal cancer can be performed safely in patients with severe chronic heart failure.