TY - JOUR T1 - Prognosis of Patients with Gastric Carcinoma Treated in Remote Island Hospitals in Japan: A Multivariable Analysis JF - Anticancer Research JO - Anticancer Res SP - 3621 LP - 3625 VL - 26 IS - 5B AU - MAKOTO TONERI AU - YOJIRO MITSUMOTO AU - MORIKAZU SHIMABUKURO AU - TSUYOSHI SUNAGAWA AU - TETSUYA ITAGAKI AU - SHINYA IIDA AU - TAICHI KONDO AU - KOSHO MATSUURA AU - JUNICHI OKEDA AU - DIPOK KUMAR DHAR Y1 - 2006/09/01 UR - http://ar.iiarjournals.org/content/26/5B/3621.abstract N2 - Background: Treating gastric cancer in remote island hospitals remains a major clinical challenge. Factors affecting prognosis of patients treated in general hospitals are still at large. We sought to determine the characteristics of gastric cancer in the Amamiooshima (Amami) archipelago of Japan and also evaluated the independent prognostic factors by the Cox regression analysis. Materials and Methods: A total of 125 patients treated in four sister hospitals in the Amami were analyzed. Results: The median age of patients with resection was 74 years and almost 85% patients had diffuse type of cancer. The 5-year overall survival was 34% for all patients and 58% for those who had a resection. Among the several clinicopathological factors, operation method (distal vs. total gastrectomy), splenectomy, lymphatic and venous invasion, T-stage, metastatic lymph node (MLN) size n-stage and UICC N-stage had significant impact on survival. Only MLN size and intraoperative blood loss had independent effect on survival by multivariable analysis. Conclusion: Improved perioperative care may yield a reasonable patient survival in elderly patients with gastric carcinoma treated in remote hospitals. Restricting amount of intraoperative blood loss may further improve the patient prognosis and MLN size may serve as a new metric to stage gastric cancers. ER -