RT Journal Article
SR Electronic
T1 Safety of Laparoscopic Gastrectomy for Advanced Gastric Cancer With Greater than Serosal Invasion Depth
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3145
OP 3152
DO 10.21873/anticanres.16487
VO 43
IS 7
A1 KANAJI, SHINGO
A1 URAKAWA, NAOKI
A1 MUKOYAMA, TOMOSUKE
A1 HARADA, HITOSHI
A1 KATO, TAKASHI
A1 GOTO, HIRONOBU
A1 YAMASHITA, KIMIHIRO
A1 MATSUDA, TAKERU
A1 OSHIKIRI, TARO
A1 KAKEJI, YOSHIHIRO
YR 2023
UL http://ar.iiarjournals.org/content/43/7/3145.abstract
AB Background/Aim: There are several concerns about oncological contamination and technical difficulty in the laparoscopic approach for locally advanced gastric cancer. We aimed to determine the safety and usefulness of laparoscopic gastrectomy for patients with advanced gastric cancer with tumor depth greater than serosal invasion. Patients and Methods: Sixty-two laparoscopic and 82 laparotomy gastric cancer cases surgically diagnosed as serosal or other organ invasions intraoperatively between 2011 and 2021 were included. The laparoscopic and open gastrectomy results were compared by propensity score matching using stage, preoperative chemotherapy, curative resection, surgical technique, and age as explanatory variables and laparoscopy and open resection as outcome variables. Results: No difference in median operative time (341 vs. 386 minutes, p=0.24) was observed, but median blood loss (0 vs. 510 ml, p<0.001) and blood transfusion requirement (9.5 vs. 43%, p<0.001) were lower in the laparoscopic group. No difference was observed between the two groups regarding complications. Furthermore, 3-year overall survival was also similar (43 vs. 42%, p=0.74). Conclusion: The laparoscopic surgery results are comparable to those of open surgery in treating gastric cancer with T4a or greater depth. In addition, it is minimally invasive with less blood loss, making it a standard approach.