TY - JOUR T1 - Surgical Treatments for Ductal Carcinoma <em>In Situ</em> (DCIS) in Elderly Patients JF - Anticancer Research JO - Anticancer Res SP - 1555 LP - 1562 DO - 10.21873/anticanres.16305 VL - 43 IS - 4 AU - ORESTE CLAUDIO BUONOMO AU - MARCO PELLICCIARO AU - MARCO MATERAZZO AU - SIMONE BERARDI AU - PAOLA ELDA GIGLIOTTI AU - JONATHAN CASPI AU - ROSARIA MEUCCI AU - TOMMASO PERRETTA AU - ILARIA PORTARENA AU - MARIO DAURI AU - CHIARA ADRIANA PISTOLESE AU - GIANLUCA VANNI Y1 - 2023/04/01 UR - http://ar.iiarjournals.org/content/43/4/1555.abstract N2 - Background/Aim: Despite an aging population, there is no consensus regarding ductal carcinoma in situ (DCIS) treatment for elderly women. Breast surgery can be well tolerated even in elderly patients. The aim of this study is to evaluate the surgical management of DCIS in elderly patients. Patients and Methods: We retrospectively analyzed patients with DCIS from 2016 to 2022 at our Breast Unit and divided our population according to age. Results: Out of 231 patients with DCIS, 45 (19.5%) were elderly. The Charlson comorbidity index and American Society of Anesthesiology (ASA) score was significantly higher in the elderly (p&lt;0.001 for both). Among the elderly, 10 (22.2%) patients received upstaging diagnoses, versus 18 (9.7%) in the control (p=0.048). Twelve (26.7%) of the elderly patients underwent sentinel lymph node biopsy, versus 93 (50%) in the control group (p=0.005). No difference was reported between groups in terms of breast conserving surgeries performed. A higher incidence of surgeries performed using local anesthesia was reported in the elderly group (p=0.041). Thirty-day surgical complications, according to Clavien-Dindo, did not show significant differences. Conclusion: Despite higher comorbidity and ASA score, breast surgery is safe and feasible in elderly patients. Due to the higher risk of upstaging to invasive ductal carcinoma, surgery should be performed but sentinel lymph node biopsy should be omitted, owing to the low risk of lymph node metastasis and lower use of adjuvant treatments. ER -