RT Journal Article
SR Electronic
T1 Comparison of Three Survival Scores in a Series of Patients ≥80 Years of Age Irradiated for Bone Metastases
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 801
OP 807
DO 10.21873/anticanres.16221
VO 43
IS 2
A1 RADES, DIRK
A1 DELIKANLI, CANSU
A1 SCHILD, STEVEN E.
A1 KRISTIANSEN, CHARLOTTE
A1 TVILSTED, SOREN
A1 JANSSEN, STEFAN
YR 2023
UL http://ar.iiarjournals.org/content/43/2/801.abstract
AB Background/Aim: Very elderly patients irradiated for bone metastases likely benefit from individualized treatments. A specific survival score was created for this group and compared to existing instruments. Patients and Methods: Ninety-six patients aged 80+ irradiated for bone metastases were retrospectively evaluated. Dose-fractionation regimen plus twelve characteristics were evaluated for survival. Results: In the Cox regression model, performance status and tumor type were significant and used for the score, which included three groups (5–7, 8–12, and 14 points) with 6-month survival rates of 15%, 52%, and 90%. Positive predictive values (PPVs) regarding death ≤6 months were 85% (new score), 100% (previous 65+ score), and 84% (previous score for any age). The new instrument and the 65+ score were also very accurate regarding survival. Since PPV regarding death was calculated from only four patients for the 65+ score, this PPV may be less conclusive than that for the new instrument. Conclusion: The new score appears useful for patients aged 80+ irradiated for bone metastases.