RT Journal Article SR Electronic T1 S-PI-RADS and PI-RRADS for Biparametric MRI in the Detection of Prostate Cancer and Post-treatment Local Recurrence JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 297 OP 303 DO 10.21873/anticanres.16163 VO 43 IS 1 A1 SCIALPI, MICHELE A1 MARTORANA, EUGENIO A1 SCIALPI, PIETRO A1 SCALERA, GIOVANNI BATTISTA A1 BELATTI, EUGENIO A1 AISA, MARIA CRISTINA A1 D’ANDREA, ALFREDO A1 MANCIOLI, FRANCESCO MARIA A1 DI MARZO, ALESSANDRO A1 TRIPPA, FABIO A1 DI BLASI, ALDO YR 2023 UL http://ar.iiarjournals.org/content/43/1/297.abstract AB The application of biparametric magnetic resonance imaging (bpMRI) [T2-weighted (T2W) and diffusion weighted imaging (DWI)/apparent diffusion coefficient (ADC)] using dedicated structured methods, such as Simplified Prostate Imaging Reporting and Data System (S-PI-RADS) for the detection, categorization, and management of prostate cancer (PCa) is reported. Also, Prostate Imaging Reporting for Local Recurrence and Data System (PI-RRADS) for the detection and assessment of the probability of local recurrence after radiotherapy (RT) or radical prostatectomy (RP) in patients with biochemical recurrence (BCR) is proposed. Both S-PI-RADS and PI-RRADS assign to DWI/ADC a main role for the above purpose. S-PI-RADS identifies four categories and, on the basis of the qualitative and quantitative analysis of the restricted diffusion on ADC map and lesion volume, distinguishes two categories of lesions: category 3 (moderately homogeneous hypointense on ADC map) and category 4 (markedly homogeneous or inhomogeneous hypointense on ADC map). In category 3, two subcategories (3a: volume <0.5 cm3 and 3b: volume ≥0.5 cm3) suggesting clinical management. PI-RRADS distinguishes four assessment categories and suggests the stratification of the probability (ranging from very low for category 1 to very high for category 4) of local disease recurrence. In clinical practice, S-PI-RADS and PI-RRADS, based on bpMRI represent a potential valid approach that may facilitates the detection and management of PCa and for detecting local recurrence after treatment improving communication with other professionals.