RT Journal Article SR Electronic T1 The Clinical Impact of Other Primary Cancer in Patients Who Received Curative Treatment for Esophageal Cancer JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 5635 OP 5641 DO 10.21873/anticanres.16072 VO 42 IS 11 A1 TORU AOYAMA A1 YUKIO MAEZAWA A1 KENTARO HARA A1 MIWHA JU A1 KEISUKE KOMORI A1 HIROSHI TAMAGAWA A1 AYAKO TAMAGAWA A1 KEISUKE KAZAMA A1 SHO SAWAZAKI A1 ITARU HASHIMOTO A1 KAZUKI KANO A1 HARUHIKO CHO A1 JUNYA MORITA A1 KENKI SEGAMI A1 TETSUSHI ISHIGURO A1 TSUTOMU SATO A1 TAKASHI OSHIMA A1 NORIO YUKAWA A1 YASUSHI RINO YR 2022 UL http://ar.iiarjournals.org/content/42/11/5635.abstract AB Background/Aim: The present study evaluated the clinical impact of other metachronous or synchronous primary cancer (OPC) in patients who received curative treatment for esophageal cancer. Patients and Methods: The present study included 168 patients who underwent curative treatment for esophageal cancer between 2005 and 2018. Prognosis and differences between the OPC status (metachronous/synchronous) and clinic pathological parameters was analyzed. Results: A total of 168 patients were included in this study. Forty patients were diagnosed with metachronous/synchronous OPC. When comparing the clinicopathological factors between the patients with and without OPC, the patients’ background and postoperative clinical courses were very similar between the two groups. The 3- and 5-year overall survival rates in patients with esophageal cancer with OPC were 66.0% and 54.5%, respectively, while those in patients without OPC were 50.1% and 41.4%, respectively. There was no statistically significant difference in these rates (p=0.156). The OPC status was not included in the final multivariate analysis model. Conclusion: The OPC status was not found to be a prognostic factor for patients who received curative treatment for esophageal cancer. Therefore, it is not necessary to avoid performing curative treatment for esophageal cancer because of a patient’s OPC status.