RT Journal Article
SR Electronic
T1 Clinicopathological Properties of Poorly-differentiated Adenocarcinoma of the Stomach: Comparison of Solid- and Non-solid-types
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 639
OP 646
VO 26
IS 1B
A1 KUNISAKI, CHIKARA
A1 AKIYAMA, HIROTOSHI
A1 NOMURA, MASATO
A1 MATSUDA, GORO
A1 OTSUKA, YUICHI
A1 ONO, HIDETAKA ANDREW
A1 NAGAHORI, YUTAKA
A1 TAKAHASHI, MASAZUMI
A1 KITO, FUMIHIKO
A1 SHIMADA, HIROSHI
YR 2006
UL http://ar.iiarjournals.org/content/26/1B/639.abstract
AB Background: The purpose of this study was to clarify the clinicopathological and biological properties of the poorly-differentiated types of gastric carcinoma (solid-type and non-solid-type). Patients and Methods: A total of 1,558 patients with primary gastric adenocarcinomas were enrolled in this study. The surgical results were compared. Results: Patients with non-solid-type tumors tended to be younger females with peritoneal or lymph node metastases and lymphatic invasion, and with tumors that were ill-defined, of larger diameter and deeper. Those patients with differentiated tumors tended to have the opposite characteristics of those patients with non-solid-type tumors. Patients with solid-type tumors had intermediate characteristics. The survival in patients with non-solid-type tumors was poor compared to those with differentiated or solid-type tumors. There was a significant difference in the survival of stage III tumors with either solid- or non-solid-type tumors (p=0.0480). Conclusion: Therapeutic strategies should be based on the histological type of the tumor in patients with poorly-differentiated gastric adenocarcinoma. Copyright© 2006 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved