PT  - JOURNAL ARTICLE
AU  - KUNISAKI, CHIKARA
AU  - AKIYAMA, HIROTOSHI
AU  - NOMURA, MASATO
AU  - MATSUDA, GORO
AU  - OTSUKA, YUICHI
AU  - ONO, HIDETAKA ANDREW
AU  - NAGAHORI, YUTAKA
AU  - TAKAHASHI, MASAZUMI
AU  - KITO, FUMIHIKO
AU  - SHIMADA, HIROSHI
TI  - Clinicopathological Properties of Poorly-differentiated Adenocarcinoma of the Stomach: Comparison of Solid- and Non-solid-types
DP  - 2006 Jan 01
TA  - Anticancer Research
PG  - 639--646
VI  - 26
IP  - 1B
4099  - http://ar.iiarjournals.org/content/26/1B/639.short
4100  - http://ar.iiarjournals.org/content/26/1B/639.full
SO  - Anticancer Res2006 Jan 01; 26
AB  - Background: The purpose of this study was to clarify the clinicopathological and biological properties of the poorly-differentiated types of gastric carcinoma (solid-type and non-solid-type). Patients and Methods: A total of 1,558 patients with primary gastric adenocarcinomas were enrolled in this study. The surgical results were compared. Results: Patients with non-solid-type tumors tended to be younger females with peritoneal or lymph node metastases and lymphatic invasion, and with tumors that were ill-defined, of larger diameter and deeper. Those patients with differentiated tumors tended to have the opposite characteristics of those patients with non-solid-type tumors. Patients with solid-type tumors had intermediate characteristics. The survival in patients with non-solid-type tumors was poor compared to those with differentiated or solid-type tumors. There was a significant difference in the survival of stage III tumors with either solid- or non-solid-type tumors (p=0.0480). Conclusion: Therapeutic strategies should be based on the histological type of the tumor in patients with poorly-differentiated gastric adenocarcinoma. Copyright© 2006 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved