TY - JOUR T1 - Liberal Application of Portal Vein Embolization for Right Hepatectomy Against Hepatocellular Carcinoma: Strategy to Achieve Zero Mortality for a Damaged Liver JF - Anticancer Research JO - Anticancer Res SP - 4089 LP - 4095 DO - 10.21873/anticanres.15906 VL - 42 IS - 8 AU - NOBUHISA SHIRAHAMA AU - YUICHI GOTO AU - HISAMUNE SAKAI AU - SHOGO FUKUTOMI AU - MASANORI AKASHI AU - TOSHIHIRO SATO AU - YOSHITO AKAGI AU - KOJI OKUDA AU - TORU HISAKA Y1 - 2022/08/01 UR - http://ar.iiarjournals.org/content/42/8/4089.abstract N2 - Background/Aim: Right hepatectomy and extended right hepatectomy (Rt-Hr) are identified as risk factors for the development of post-hepatectomy liver failure (PHLF). Although portal vein embolization (PVE) has made it possible to safely perform extended hepatectomy, to ensure safety, in our department, PVE is performed prior to Rt-Hr for hepatocellular carcinoma (HCC) regardless of the resection rate. This study aimed to retrospectively investigate the clinical course of PVE prior to Rt-Hr for HCC cases resected in our department and the appropriateness of our policy by clarifying complications and deaths. Patients and Methods: The target period was from 2005 to 2020. Among the HCC cases resected at our hospital, those in which PVE was performed prior to Rt-Hr were included in this study. For PHLF, the definition of the International Study Group of Liver Surgery was used. The Clavien-Dindo classification was used for postoperative complications. Perioperative mortality was defined as the overall mortality within 30 days following surgery and surgery-related deaths within 90 days following surgery. Results: A total of 79 cases were included. Rt-Hr was possible in all cases after PVE and there were no cases in which serious complications occurred after PVE. PHLF was found in 14 cases (17.7%)/5 cases (6.4%)/0 cases (0%) of Grade A/B/C, respectively. Regarding postoperative complications, there were no Grade IV, and Grade IIIa/IIIb were found in 13 cases (16.5%). There were no perioperative deaths. Conclusion: Our department’s policy of performing PVE prior to all Rt-Hr was considered to be a safe and reasonable treatment strategy. ER -