RT Journal Article
SR Electronic
T1 Successful Treatment of Intrahepatic Cholangiocarcinoma With Liver/Lung Metastasis and Peritoneal Dissemination After Liver Resection
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 3209
OP 3215
DO 10.21873/anticanres.15811
VO 42
IS 6
A1 KAZUKI MATSUMURA
A1 KENSUKE YAMAMURA
A1 ERI ODA
A1 SHINICHI AKAHOSHI
A1 TAKATOSHI ISHIKO
A1 TATSUNORI MIYATA
A1 HIDEAKI MIYAMOTO
A1 TOSHIHIKO MOTOHARA
A1 AKIRA SASAO
A1 YOSHIHIRO KOMOHARA
A1 HIDECHIKA KAWANO
A1 TORU BEPPU
YR 2022
UL http://ar.iiarjournals.org/content/42/6/3209.abstract
AB Background/Aim: Intrahepatic cholangiocarcinoma (ICC) is increasing in incidence and has a poor prognosis. Case Report: A 79-year-old woman with two liver tumors was referred to our institution. The tumors demonstrated irregular margins and continuous peripheral enhancement. She had a good liver function and an elevated CA19-9 level. Extended left hepatectomy, and partial hepatectomy was performed. The patient was diagnosed with poorly differentiated ICC. Two lung metastases, one liver metastasis, and localized intraperitoneal dissemination occurred 19, 24, and 32 months after the initial hepatectomy. The lung metastases were treated with computed tomography-guided radiofrequency ablation approximately after one year of observation. The liver metastasis was resected immediately. The peritoneal dissemination was removed entirely after effective 3-month chemotherapy using gemcitabine and S-1. The patient is alive with no tumor 44 months after the first surgery. Conclusion: Multidisciplinary treatment considering a metastatic site and tumor malignancy might be effective for patients with ICC who have multiple recurrences.