RT Journal Article
SR Electronic
T1 Prognostic Value of the Regional Lymph Node Station in Pancreatic Neuroendocrine Tumor
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 2797
OP 2801
DO 10.21873/anticanres.15760
VO 42
IS 5
A1 KOSEI TAKAGI
A1 YUZO UMEDA
A1 RYUICHI YOSHIDA
A1 KAZUHIRO YOSHIDA
A1 TOMOKAZU FUJI
A1 KENJIRO KUMANO
A1 KAZUYA YASUI
A1 TAKAHITO YAGI
A1 TOSHIYOSHI FUJIWARA
YR 2022
UL http://ar.iiarjournals.org/content/42/5/2797.abstract
AB Background/Aim: Little is known regarding the impact of lymph node dissection on survival benefit after curative resection for pancreatic neuroendocrine tumor (PNET). This study aimed to evaluate the efficacy of lymph node dissection based on tumor location of PNET. Patients and Methods: A retrospective study, including 50 patients with surgical resection for PNET between 2004 and 2020, was performed. The efficacy index (EI) was calculated by multiplication of the incidence of lymph node metastasis (LNM) at the station and the 5-year survival rate of patients with LNM at the station. Results: In the pancreatic head tumors, the peri-pancreatic head and superior mesenteric artery lymph node stations had high EI of 13.3 and 25, respectively. In contrast, other stations, including stations 8 and 12, had zero EI. In the pancreatic body and tail tumors, only the splenic artery lymph node station had a survival benefit from lymph node dissection with an EI of 6.7. Conclusion: The extent of lymph node dissection for PNET should be decided based on the efficacy of lymph node dissection in accordance with tumor location. Our findings may be helpful in determining the extent of lymph node dissection required.