RT Journal Article
SR Electronic
T1 Clinical Outcomes of Esophagectomy and Chemoradiotherapy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 2791
OP 2795
DO 10.21873/anticanres.15759
VO 42
IS 5
A1 EMI, MANABU
A1 HMAI, YOICHI
A1 YOSHIKAWA, TORU
A1 HIROHATA, RYOSUKE
A1 OSAWA, MANATO
A1 OKADA, MORIHITO
A1 MURAKAMI, YUJI
A1 NISHIBUCHI, IKUNO
YR 2022
UL http://ar.iiarjournals.org/content/42/5/2791.abstract
AB Background/Aim: Surgical resection and chemoradiotherapy (CRT) can be performed as additional treatments for superficial esophageal cancer after endoscopic resection, but the selection criteria vary depending on the institution. We retrospectively evaluated the outcomes of patients with endoscopically resected superficial esophageal cancer treated with surgical resection and CRT at our institution. Patients and Methods: The outcomes of 67 cases of additional treatment after endoscopic resection of superficial esophageal cancer, excluding adenocarcinoma, performed at our hospital from January 2000 to June 2017 were compared (30 cases in the surgery group and 37 cases in the CRT group). Results: In the surgery group, eight patients had lymph node metastasis and two had recurrence in the supraclavicular fossa lymph nodes after surgery, therefore reoperation was performed. There were no deaths from esophageal cancer, and the 5-year survival rate was 92.6%. One patient in the CRT group had a recurrence in the cervical paraoesophageal lymph node, which was resected, but no death from esophageal cancer was observed, and the 5-year survival rate was 81.0%. The 5-year survival rate was significantly better in the surgery group than in the CRT group (p=0.039). The greater number of elderly patients in the CRT group was considered to be the reason for the worse prognosis, Conclusion: Although the prognosis of esophagectomy or chemoradiotherapy (CRT) is very favorable, CRT is considered to be the preferred additional treatment after endoscopic resection of superficial esophageal cancer without lymph node metastasis from the viewpoint of organ preservation.