PT  - JOURNAL ARTICLE
AU  - MANABU EMI
AU  - YOICHI HMAI
AU  - TORU YOSHIKAWA
AU  - RYOSUKE HIROHATA
AU  - MANATO OSAWA
AU  - MORIHITO OKADA
AU  - YUJI MURAKAMI
AU  - IKUNO NISHIBUCHI
TI  - Clinical Outcomes of Esophagectomy and Chemoradiotherapy After Endoscopic Resection for Superficial Esophageal Squamous Cell Carcinoma
AID  - 10.21873/anticanres.15759
DP  - 2022 May 01
TA  - Anticancer Research
PG  - 2791--2795
VI  - 42
IP  - 5
4099  - http://ar.iiarjournals.org/content/42/5/2791.short
4100  - http://ar.iiarjournals.org/content/42/5/2791.full
SO  - Anticancer Res2022 May 01; 42
AB  - Background/Aim: Surgical resection and chemoradiotherapy (CRT) can be performed as additional treatments for superficial esophageal cancer after endoscopic resection, but the selection criteria vary depending on the institution. We retrospectively evaluated the outcomes of patients with endoscopically resected superficial esophageal cancer treated with surgical resection and CRT at our institution. Patients and Methods: The outcomes of 67 cases of additional treatment after endoscopic resection of superficial esophageal cancer, excluding adenocarcinoma, performed at our hospital from January 2000 to June 2017 were compared (30 cases in the surgery group and 37 cases in the CRT group). Results: In the surgery group, eight patients had lymph node metastasis and two had recurrence in the supraclavicular fossa lymph nodes after surgery, therefore reoperation was performed. There were no deaths from esophageal cancer, and the 5-year survival rate was 92.6%. One patient in the CRT group had a recurrence in the cervical paraoesophageal lymph node, which was resected, but no death from esophageal cancer was observed, and the 5-year survival rate was 81.0%. The 5-year survival rate was significantly better in the surgery group than in the CRT group (p=0.039). The greater number of elderly patients in the CRT group was considered to be the reason for the worse prognosis, Conclusion: Although the prognosis of esophagectomy or chemoradiotherapy (CRT) is very favorable, CRT is considered to be the preferred additional treatment after endoscopic resection of superficial esophageal cancer without lymph node metastasis from the viewpoint of organ preservation.