PT  - JOURNAL ARTICLE
AU  - HIROFUMI MATSUOKA
AU  - KEIICHIRO NAKAMURA
AU  - YUKO MATSUBARA
AU  - NAOYUKI IDA
AU  - TAKESHI NISHIDA
AU  - CHIKAKO OGAWA
AU  - KUNIAKI KATSI
AU  - SUSUMU KANAZAWA
AU  - HISASHI MASUYAMA
TI  - Sarcopenia Is Not a Prognostic Factor of Outcome in Patients With Cervical Cancer Undergoing Concurrent Chemoradiotherapy or Radiotherapy
AID  - 10.21873/anticanres.13196
DP  - 2019 Feb 01
TA  - Anticancer Research
PG  - 933--939
VI  - 39
IP  - 2
4099  - http://ar.iiarjournals.org/content/39/2/933.short
4100  - http://ar.iiarjournals.org/content/39/2/933.full
SO  - Anticancer Res2019 Feb 01; 39
AB  - Background/Aim: The objective of this study was to determine if sarcopenia was a predictor of poor prognosis in patients with cervical cancer (CC) undergoing concurrent chemoradiation therapy (CCRT) or radiation therapy (RT). Materials and Methods: A total of 236 patients with CC undergoing CCRT or RT were retrospectively examined. We determined if clinical characteristics and survival were correlated with pretreatment sarcopenia, measured as psoas muscle index (PI) or skeletal muscle index (SMI). Results: Pretreatment PI and SMI were related to parametrial involvement with CC undergoing CCRT or RT (p=0.002, and, p=0.034, respectively). The median progression-free survival (PFS) and overall survival (OS) times in patients undergoing CCRT or RT were 29.0 and 34.5 months, respectively. Neither PI nor SMI were prognostic predictors in patients with CC undergoing CCRT or RT. Conclusion: Sarcopenia is not a predictive factor of outcome in patients with CC undergoing CCRT or RT.