RT Journal Article SR Electronic T1 Improving Breast Conserving Surgery Using the Faxitron® OR Specimen Radiography System – A Complication Analysis, Cost Evaluation and Literature Review JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 1925 OP 1932 DO 10.21873/anticanres.15670 VO 42 IS 4 A1 EICHLER, CHRISTIAN A1 WESTERHOFF, ANKE A1 WARM, MATHIAS A1 HANSTEIN, BETTINA A1 PUPPE, JULIAN A1 KRUG, BARBARA A1 MALTER, WOLFRAM YR 2022 UL http://ar.iiarjournals.org/content/42/4/1925.abstract AB Background/Aim: The combination of pre-surgical clip placement and hook-wire guided surgery is considered the gold standard for adequately locating non-palpable lesions during breast conserving surgery. After surgical removal of the segment, radiography is required to confirm clip removal, increasing surgical time, post-surgical complication rates, and cost. Patients and Methods: We performed a retrospective analysis, using the Faxitron® in-theater specimen radiography system, of the following primary endpoints: surgical time and complication rates. The secondary endpoints were cost effectiveness and clip-location rates. The Control cohort included breast conserving surgery patients prior to May 2019 (n=150) and the Validation cohort included breast conserving surgery patients after May 2019 (n=53). Results: The analysis showed an improvement in surgical time when using the Faxitron® system, which is directly linked to a benefit in cost effectiveness. A numerical benefit in complication rates was also shown. A subgroup analysis showed a significant advantage in surgical time for breast conserving surgery plus sentinel node biopsy and open breast biopsies. Conclusion: Use of the Faxitron® system significantly reduces surgical time, which increases cost efficiency while maintaining a low complication rate.