PT  - JOURNAL ARTICLE
AU  - EICHLER, CHRISTIAN
AU  - WESTERHOFF, ANKE
AU  - WARM, MATHIAS
AU  - HANSTEIN, BETTINA
AU  - PUPPE, JULIAN
AU  - KRUG, BARBARA
AU  - MALTER, WOLFRAM
TI  - Improving Breast Conserving Surgery Using the Faxitron<sup>®</sup> OR Specimen Radiography System – A Complication Analysis, Cost Evaluation and Literature Review
AID  - 10.21873/anticanres.15670
DP  - 2022 Apr 01
TA  - Anticancer Research
PG  - 1925--1932
VI  - 42
IP  - 4
4099  - http://ar.iiarjournals.org/content/42/4/1925.short
4100  - http://ar.iiarjournals.org/content/42/4/1925.full
SO  - Anticancer Res2022 Apr 01; 42
AB  - Background/Aim: The combination of pre-surgical clip placement and hook-wire guided surgery is considered the gold standard for adequately locating non-palpable lesions during breast conserving surgery. After surgical removal of the segment, radiography is required to confirm clip removal, increasing surgical time, post-surgical complication rates, and cost. Patients and Methods: We performed a retrospective analysis, using the Faxitron® in-theater specimen radiography system, of the following primary endpoints: surgical time and complication rates. The secondary endpoints were cost effectiveness and clip-location rates. The Control cohort included breast conserving surgery patients prior to May 2019 (n=150) and the Validation cohort included breast conserving surgery patients after May 2019 (n=53). Results: The analysis showed an improvement in surgical time when using the Faxitron® system, which is directly linked to a benefit in cost effectiveness. A numerical benefit in complication rates was also shown. A subgroup analysis showed a significant advantage in surgical time for breast conserving surgery plus sentinel node biopsy and open breast biopsies. Conclusion: Use of the Faxitron® system significantly reduces surgical time, which increases cost efficiency while maintaining a low complication rate.