RT Journal Article SR Electronic T1 Partial Resection of the Sternum for Osseous Metastasis of Differentiated Thyroid Cancer: Case Report JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4389 OP 4392 VO 25 IS 6C A1 MEYER, ANDREAS A1 BEHREND, MATTHIAS YR 2005 UL http://ar.iiarjournals.org/content/25/6C/4389.abstract AB Background: Due to their resistance to radio-iodine therapy, skeletal metastases from differentiated thyroid cancer (DTC) are difficult to treat. Surgical resection of solitary skeletal metastasis may offer cure with prolonged survival. Case Report: A patient with the simultaneous appearance of local recurrence of DTC and skeletal metastasis of the cranial sternum is reported. After radical excision of the tumour recurrence and the lymph nodes, a partial sternal resection was carried out, and the defect in the chest wall was reconstructed with polypropylene mesh. Radio-iodine ablation therapy was carried out 4 times after the operation for locally recurrent disease. At the follow-up, 4½ years after the resection of the sternal metastasis, the patient is free of disease. Conclusion: Sternal resection for solitary osseous metastasis of DTC should be performed on selected, individual patients. Reconstruction of the sternum with polypropylene mesh, as a simple and effective method, produces satisfactory functional and cosmetic results and allows a more effective radio-iodine treatment. Copyright© 2005 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved