PT  - JOURNAL ARTICLE
AU  - MEYER, ANDREAS
AU  - BEHREND, MATTHIAS
TI  - Partial Resection of the Sternum for Osseous Metastasis of Differentiated Thyroid Cancer: Case Report
DP  - 2005 Nov 01
TA  - Anticancer Research
PG  - 4389--4392
VI  - 25
IP  - 6C
4099  - http://ar.iiarjournals.org/content/25/6C/4389.short
4100  - http://ar.iiarjournals.org/content/25/6C/4389.full
SO  - Anticancer Res2005 Nov 01; 25
AB  - Background: Due to their resistance to radio-iodine therapy, skeletal metastases from differentiated thyroid cancer (DTC) are difficult to treat. Surgical resection of solitary skeletal metastasis may offer cure with prolonged survival. Case Report: A patient with the simultaneous appearance of local recurrence of DTC and skeletal metastasis of the cranial sternum is reported. After radical excision of the tumour recurrence and the lymph nodes, a partial sternal resection was carried out, and the defect in the chest wall was reconstructed with polypropylene mesh. Radio-iodine ablation therapy was carried out 4 times after the operation for locally recurrent disease. At the follow-up, 4½ years after the resection of the sternal metastasis, the patient is free of disease. Conclusion: Sternal resection for solitary osseous metastasis of DTC should be performed on selected, individual patients. Reconstruction of the sternum with polypropylene mesh, as a simple and effective method, produces satisfactory functional and cosmetic results and allows a more effective radio-iodine treatment. Copyright© 2005 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved