PT - JOURNAL ARTICLE AU - SHOTA IKE AU - MASATAKE MATSUOKA AU - TOMOHIRO ONODERA AU - ISAO YOKOTA AU - KOJI IWASAKI AU - RYOSUKE HISHIMURA AU - YUKI SUZUKI AU - EIJI KONDO AU - NORIMASA IWASAKI TI - Primary Malignant Osseous Neoplasms in the Hand AID - 10.21873/anticanres.15639 DP - 2022 Mar 01 TA - Anticancer Research PG - 1635--1640 VI - 42 IP - 3 4099 - http://ar.iiarjournals.org/content/42/3/1635.short 4100 - http://ar.iiarjournals.org/content/42/3/1635.full SO - Anticancer Res2022 Mar 01; 42 AB - Background: Primary malignant osseous neoplasms of the hand are rare malignancies. Comprehensive demographic and survival data regarding primary malignant osseous neoplasms of the hand are lacking in the literature. Patients and Methods: Using the Surveillance, Epidemiology, and End Results (SEER) database, we identified all patients with primary malignant osseous neoplasms of the hand diagnosed between 1983 and 2015. Demographic data were searched for primary osseous neoplasms in the hand and higher incidence of histological subtype. Results: A total of 197 patients were analyzed: 103 patients were diagnosed with histologically low-grade tumor, and 31 were diagnosed with high-grade tumor. Five-year cancer-specific and overall survival rates for the entire cohort were 91.4% and 81.9%, respectively. Histological high tumor grade and regional stage from SEER historic stage data were associated with unfavorable cancer-specific survival. Conclusion: Special caution is required if patients have histologically high-grade tumor or tumor extending beyond the periosteum into surrounding joints, as these features worsen cancer-specific mortality.