TY - JOUR T1 - A Case of Salvage Maxillectomy for Recurrent Oral Cancer After Boron Neutron Capture Therapy During the COVID-19 Pandemic JF - Anticancer Research JO - Anticancer Res SP - 1653 LP - 1657 DO - 10.21873/anticanres.15642 VL - 42 IS - 3 AU - HIDENORI SUZUKI AU - MAI YOKOI AU - SUMITAKA HAGIWARA AU - EIICHI SASAKI AU - YOSHIAKI KOBAYASHI AU - SHO IWAKI AU - DAISUKE NISHIKAWA AU - SHINTARO BEPPU AU - HOSHINO TERADA AU - MICHI SAWABE AU - NOBUHIRO HANAI Y1 - 2022/03/01 UR - http://ar.iiarjournals.org/content/42/3/1653.abstract N2 - Background: During the COVID-19 pandemic, pedicle flaps instead of free flap transfer were recommended for head and neck reconstruction to reduce infection risk. Boron neutron-capture therapy in Japan was clinically approved in 2020 as a salvage radiotherapy for recurrent head and neck cancer following chemoradiotherapy. The efficacy and safety of salvage surgery following boron neutron-capture therapy remain unclear. Case Report: We describe a 57-year-old male with crT4aN0M0 oral cancer after three different forms of radiotherapy including boron neutron-capture therapy, treated by salvage partial maxillectomy with both buccal fat pad and nasoseptal flaps. His postsurgical course was successful, without tracheostomy, and he had no Clavien– Dindo grade 3 or 4 complications. The pathological diagnosis was T4a squamous cell carcinoma with a negative surgical margin. No recurrence or metastasis had occurred at 113 days postoperatively. No opioid consumption was needed postoperatively. Conclusion: Pathological negative margins were achieved in this case and there were no severe complications. Further accrual of cases salvage surgery following boron neutron-capture therapy is required to clarify treatment strategies for recurrent head and neck cancer. ER -