PT  - JOURNAL ARTICLE
AU  - MATSUDA, RYOSUKE
AU  - KOTSUGI, MASASHI
AU  - NAKASE, KENTA
AU  - MORIMOTO, TAKAYUKI
AU  - NISHIMURA, FUMIHIKO
AU  - NAKAGAWA, ICHIRO
AU  - NAKASE, HIROYUKI
TI  - Awake Craniotomy for Subcortical Brain Metastasis Beneath the Speech Center: A Technical Case Report
AID  - 10.21873/anticanres.15640
DP  - 2022 Mar 01
TA  - Anticancer Research
PG  - 1641--1644
VI  - 42
IP  - 3
4099  - http://ar.iiarjournals.org/content/42/3/1641.short
4100  - http://ar.iiarjournals.org/content/42/3/1641.full
SO  - Anticancer Res2022 Mar 01; 42
AB  - Background: To preserve language function, intraoperative functional brain mapping (IFBM) in and near the speech center is essential. Case Report: We present a case of a 73-year-old right-handed woman with colon cancer. She presented with mild speech disturbance. Magnetic resonance imaging revealed a ringed enhancing lesion in the frontal operculum. The preservation of language function was critical; therefore, she underwent awake craniotomy using IFBM. Thus, the speech site was elicited by cortical electrical stimulation at the surface, near the location of the tumor. We made a safe corticotomy on the surface of the lesion and performed the resection of brain metastasis (BM) via a safety corridor. We achieved gross total resection of the BM while preserving the language function. After surgery, she recovered from speech disturbance. She returned to her normal life with improved language function. Conclusion: IFBM is a useful tool to undertake a safe approach via the speech center, avoiding permanent language deficits.