PT - JOURNAL ARTICLE AU - TAKUYA SHIRAISHI AU - HIROOMI OGAWA AU - NAOYA OZAWA AU - KUNIHIKO SUGA AU - CHIKA KOMINE AU - YUTA SHIBASAKI AU - KATSUYA OSONE AU - TAKUHISA OKADA AU - YASUAKI ENOKIDA AU - MAKOTO SOHDA AU - KEN SHIRABE AU - HIROSHI SAEKI TI - Risk and Protective Factors for Postoperative Complications in Elderly Patients With Colorectal Cancer AID - 10.21873/anticanres.15575 DP - 2022 Feb 01 TA - Anticancer Research PG - 1123--1130 VI - 42 IP - 2 4099 - http://ar.iiarjournals.org/content/42/2/1123.short 4100 - http://ar.iiarjournals.org/content/42/2/1123.full SO - Anticancer Res2022 Feb 01; 42 AB - Aim: This study aimed to evaluate perioperative factors, including nutritional status and sarcopenia on short-term postoperative complications, determine the risk factors for postoperative complications, and clarify potential preoperative interventions and optimal surgical procedures to improve short-term outcomes in elderly patients with colorectal cancer (CRC). Patients and Methods: This retrospective, single-centre cohort study analysed the factors and short-term postoperative complications of CRC in a cohort of 101 patients aged ≥80 years who underwent radical resection between 2013 and 2020. Nutritional status was evaluated by calculating the controlling nutritional status. Results: The median age was 83 years, and the frequency of sarcopenia was 39.6%. Short-term postoperative complications occurred in 24 patients. Risk factors for short-term postoperative complications in multivariate analysis were sarcopenia combined with nutritional disorders and open surgical approach. Conclusion: The status of nutrition and sarcopenia must be considered in order to predict and improve postoperative outcomes. If possible, a laparoscopic approach should be selected to prevent poor postoperative outcomes.