@article {FUJITA911, author = {NOBUHIRO FUJITA and ATSUHIKO HANDA and JINHA M. PARK}, title = {Peritumoral Hyperintensity at Hepatobiliary Phase Gadoxetic Acid{\textendash}enhanced MRI in Hepatic Neuroendocrine Tumors}, volume = {42}, number = {2}, pages = {911--917}, year = {2022}, doi = {10.21873/anticanres.15549}, publisher = {International Institute of Anticancer Research}, abstract = {Background/Aim: To identify the imaging and clinical features of hepatic neuroendocrine tumors (NETs) associated with peritumoral hyperintensity in the hepatobiliary phase of gadoxetic acid-enhanced magnetic resonance (MR) imaging. Patients and Methods: Fifty-seven patients with hepatic NETs were enrolled. Based on the degree of peritumoral hyperintensity, patients were divided into three groups: group 0 (no peritumoral hyperintensity), group 1 (lower peritumoral hyperintensity), and group 2 (higher peritumoral hyperintensity). The imaging and clinical findings were compared among the three groups. Results: Apparent diffusion coefficient (ADC) values of group 2 were significantly lower than those of group 0 and group 1. Atypical (cholangiocarcinoma-like) enhancement pattern in the arterial phase was significantly more frequently observed in group 2 as compared to that in group 0 and group 1. Group 2 patients showed significantly poorer progression-free survival than group 0 patients. Conclusion: Hepatic NETs with greater peritumoral hyperintensity exhibit greater malignant potential.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/42/2/911}, eprint = {https://ar.iiarjournals.org/content/42/2/911.full.pdf}, journal = {Anticancer Research} }