TY - JOUR T1 - Is Total Laparoscopic Surgery for Endometrial Carcinoma at Risk of Local Recurrence? A Long-term Survival JF - Anticancer Research JO - Anticancer Res SP - 2423 LP - 2428 VL - 25 IS - 3C AU - RENATO SERACCHIOLI AU - STEFANO VENTUROLI AU - MICHELA CECCARINI AU - MARIANNA CANTARELLI AU - MARCELLO CECCARONI AU - ELETTRA PIGNOTTI AU - DOMENICO DE ALOYSIO AU - PIERANDREA DE IACO Y1 - 2005/05/01 UR - http://ar.iiarjournals.org/content/25/3C/2423.abstract N2 - Background: Loco-regional recurrences after laparotomic surgery for early endometrial carcinoma have an incidence of 3-8%. This study examined the pattern of recurrences and survival after full laparoscopic hysterectomy. Patients and Methods: Between January 1997 and December 2002, 113 consecutive patients with pre-operative Stage I endometrial cancer, self-referred to two different surgical teams, were treated by the laparoscopic approach by one team and by the laparotomic approach by the other team. Results: Nineteen patients were treated by total laparoscopic hysterectomy (TLH) by the endoscopic group, and 94 were treated by total abdominal hysterectomy (TAH) by the oncologic group. Sixteen patients (84.2%) in the laparoscopic group and 79 patients (84.0%) in the laparotomic group had Stage I disease. The mean age and mean weight did not differ in the two groups. With a mean follow-up of 52.2 months for the TLH group and 43.6 months for the TAH group, one recurrence (5.3%) was observed in the former group and 9 recurrences (10.6%) in the latter group. No significative differences were observed for disease-free survival and overall survival. Conclusion: Total laparoscopic hysterectomy does not increase the risk of local recurrence and does not affect survival for patients with early stage endometrial carcinoma. ER -