RT Journal Article SR Electronic T1 Is Total Laparoscopic Surgery for Endometrial Carcinoma at Risk of Local Recurrence? A Long-term Survival JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 2423 OP 2428 VO 25 IS 3C A1 RENATO SERACCHIOLI A1 STEFANO VENTUROLI A1 MICHELA CECCARINI A1 MARIANNA CANTARELLI A1 MARCELLO CECCARONI A1 ELETTRA PIGNOTTI A1 DOMENICO DE ALOYSIO A1 PIERANDREA DE IACO YR 2005 UL http://ar.iiarjournals.org/content/25/3C/2423.abstract AB Background: Loco-regional recurrences after laparotomic surgery for early endometrial carcinoma have an incidence of 3-8%. This study examined the pattern of recurrences and survival after full laparoscopic hysterectomy. Patients and Methods: Between January 1997 and December 2002, 113 consecutive patients with pre-operative Stage I endometrial cancer, self-referred to two different surgical teams, were treated by the laparoscopic approach by one team and by the laparotomic approach by the other team. Results: Nineteen patients were treated by total laparoscopic hysterectomy (TLH) by the endoscopic group, and 94 were treated by total abdominal hysterectomy (TAH) by the oncologic group. Sixteen patients (84.2%) in the laparoscopic group and 79 patients (84.0%) in the laparotomic group had Stage I disease. The mean age and mean weight did not differ in the two groups. With a mean follow-up of 52.2 months for the TLH group and 43.6 months for the TAH group, one recurrence (5.3%) was observed in the former group and 9 recurrences (10.6%) in the latter group. No significative differences were observed for disease-free survival and overall survival. Conclusion: Total laparoscopic hysterectomy does not increase the risk of local recurrence and does not affect survival for patients with early stage endometrial carcinoma.