@article {COGGIN2345, author = {JOSEPH H. COGGIN, JR. and ADEL L. BARSOUM and JAMES W. ROHRER and MARTIN THURNHER and MATTHIAS ZEIS}, title = {Contemporary Definitions of Tumor Specific Antigens, Immunogens and Markers as Related to the Adaptive Responses of the Cancer-Bearing Host}, volume = {25}, number = {3C}, pages = {2345--2355}, year = {2005}, publisher = {International Institute of Anticancer Research}, abstract = {This review describes clear parameters for designating the correct use of the term Tumor Rejection Antigen [TRA] to define the role of tumor cell constituents which activate adaptive anti-tumor immune reactions in the cancer-bearing host. This is important, especially in defining immunogens which activate the patient{\textquoteright}s cytotoxic T-cells that are important to immunotherapeutic applications in human cancer treatment. The focus of the review is to correctly delineate the immunogenic properties of 37kDa oncofetal antigen [OFA], one of only a few true TRAs expressed on human and experimental rodent cancers. The purpose of this review is to provide a background for publication reviewers, journal and text editors, and scientists reporting on TRAs to avoid creating further confusion that has proliferated in the cancer literature to imply traits of so-called tumor-associated antigens that do not qualify as TRAs.}, issn = {0250-7005}, URL = {https://ar.iiarjournals.org/content/25/3C/2345}, eprint = {https://ar.iiarjournals.org/content/25/3C/2345.full.pdf}, journal = {Anticancer Research} }